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Cancer in young people is rare, but it is still a major health

issue in Europe.

Each year, more than 6,000 young people in

Europe die of cancer. There are more than 300,000 European

childhood cancer survivors (in 2020, they will be nearly half

a million): two-thirds of them have some late side effects of

treatment, that are severe and impact on the daily life of half

of those affected.

Within the European Network for Cancer research in Children

and Adolescents (ENCCA), SIOPE and the European paediatric

haematology-oncology community have established a long-

term sustainable Strategic Plan

to increase the cure rate and

the quality of survivorship for children and young people with

cancer over the next ten years.

The ultimate goal is to increase

the disease- and late-effect- free survival after 10 years from

the disease, and beyond.



Innovative treatments

: to introduce safe and effective innovative treatments (i.e. new

drugs, new technologies) into standard care;

Precision cancer medicine

: to use improved risk classification as well as biological

characteristics of both the tumour and patient (such as molecular and immunological

factors) to help guide decisions on which therapies to use;

Tumour biology

: to increase knowledge of tumour biology and speed up translation from

basic research to clinical care to benefit patients;

Equal access

: to bring about equal access across Europe to standard care (in both diagnosis

and treatment), expertise and clinical research;

Teenagers and Young Adults

: to address the specific needs of teenagers and young adults

(TYA), in cooperation with adult oncology;

Quality of survivorship

: to address the consequences of cancer treatment such as long-

term side effects, to better understand the genetic background/risk of an individual, and

to improve quality of life of survivors of childhood cancer;

Causes of cancer:

to understand the causes of paediatric cancers and to address

prevention wherever possible.

Seven medical and scientific objectives have been set up to achieve these goals:



From AIEOP. Credit Attilio Rossetti photographer, Italy